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Structure paper

TitleActivity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses?
Journal, issue, pagesTo be published
Publish dateOct 27, 2022 (structure data deposition date)
AuthorsStein CS / Hansen G / Ssebyatika GL / Stroeh L / Benecke T / Menz S / Waldmann J-Y / Vollmer B / Tipp S / Ochulor O ...Stein CS / Hansen G / Ssebyatika GL / Stroeh L / Benecke T / Menz S / Waldmann J-Y / Vollmer B / Tipp S / Ochulor O / Herold E / Schwarzloh B / Mutschall D / Zischke J-Y / Cordes A / Puppe W / Schneider T / Hinrichs I / Blasczyk R / Kleine-Weber H / Hoffmann M / Hoeper M / Kaiser FK / Gonzalez-Hernandez M / Armando FK / Ciurkiewicz M / Beythien G / Poehlmann S / Baumgaertner W / Gruenewald K / Osterhaus A / Schulz T / Krey T
External linksSearch PubMed
MethodsEM (single particle) / X-ray diffraction
Resolution1.6 - 4.11 Å
Structure data

16024

8bg6

EMDB-16024, PDB-8bg6:
SARS-CoV-2 S protein in complex with pT1644 Fab
Method: EM (single particle) / Resolution: 4.11 Å

16026

8bg8

EMDB-16026, PDB-8bg8:
SARS-CoV-2 S protein in complex with pT1696 Fab
Method: EM (single particle) / Resolution: 3.64 Å

PDB-8bec:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1375 scFV
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-8bg1:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1511 scFV
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-8bg2:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1580 scFV
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-8bg3:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1610 scFV
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-8bg4:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1611 scFV
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-8bg5:
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1631 scFV
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsPROTEIN BINDING / PROTEIN BINDING/IMMUNE SYSTEM

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