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-Structure paper
Title | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. |
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Journal, issue, pages | Sci Transl Med, Vol. 14, Page eabn0402-eabn0402, Year 2022 |
Publish date | Sep 23, 2021 (structure data deposition date) |
![]() | Crook, Z.R. / Girard, E.J. / Sevilla, G.P. / Brusniak, M.Y. / Rupert, P.B. / Friend, D.J. / Gewe, M.M. / Clarke, M. / Lin, I. / Ruff, R. ...Crook, Z.R. / Girard, E.J. / Sevilla, G.P. / Brusniak, M.Y. / Rupert, P.B. / Friend, D.J. / Gewe, M.M. / Clarke, M. / Lin, I. / Ruff, R. / Pakiam, F. / Phi, T.D. / Bandaranayake, A. / Correnti, C.E. / Mhyre, A.J. / Nairn, N.W. / Strong, R.K. / Olson, J.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.77 - 2.5 Å |
Structure data | ![]() PDB-7sao: ![]() PDB-7sap: ![]() PDB-7sgq: ![]() PDB-7sjq: ![]() PDB-7slt: ![]() PDB-7snc: ![]() PDB-7snd: |
Chemicals | ![]() ChemComp-CO: ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-NAG: ![]() ChemComp-NA: ![]() ChemComp-PO4: |
Source |
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![]() | TOXIN / CTI-homolog / pacifastin / CDP / cystine-dense peptides / CTI / Protease inhibitors / ANTITUMOR PROTEIN / PDL1 binder / protease inhibitor |