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Title | Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations. |
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Journal, issue, pages | Nat. Immunol., Vol. 22, Page 1503-1514, Year 2021 |
Publish date | Jun 4, 2021 (structure data deposition date) |
Authors | Dussupt, V. / Sankhala, R.S. / Mendez-Rivera, L. / Townsley, S.M. / Schmidt, F. / Wieczorek, L. / Lal, K.G. / Donofrio, G.C. / Tran, U. / Jackson, N.D. ...Dussupt, V. / Sankhala, R.S. / Mendez-Rivera, L. / Townsley, S.M. / Schmidt, F. / Wieczorek, L. / Lal, K.G. / Donofrio, G.C. / Tran, U. / Jackson, N.D. / Zaky, W.I. / Zemil, M. / Tritsch, S.R. / Chen, W.H. / Martinez, E.J. / Ahmed, A. / Choe, M. / Chang, W.C. / Hajduczki, A. / Jian, N. / Peterson, C.E. / Rees, P.A. / Rutkowska, M. / Slike, B.M. / Selverian, C.N. / Swafford, I. / Teng, I.T. / Thomas, P.V. / Zhou, T. / Smith, C.J. / Currier, J.R. / Kwong, P.D. / Rolland, M. / Davidson, E. / Doranz, B.J. / Mores, C.N. / Hatziioannou, T. / Reiley, W.W. / Bieniasz, P.D. / Paquin-Proulx, D. / Gromowski, G.D. / Polonis, V.R. / Michael, N.L. / Modjarrad, K. / Joyce, M.G. / Krebs, S.J. |
External links | Nat. Immunol. / PubMed:34716452 |
Methods | X-ray diffraction |
Resolution | 2.207 - 3.79 Å |
Structure data | PDB-7n4i: PDB-7n4j: PDB-7n4l: PDB-7n4m: |
Chemicals | ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN/IMMUNE SYSTEM / Neutralizing antibody / SARS-CoV-2 / WRAIR-2057 / receptor binding domain / ANTIVIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / WRAIR-2173 / WRAIR-2125 / WRAIR-2151 |