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-Structure paper
Title | Design of protein-binding proteins from the target structure alone. |
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Journal, issue, pages | Nature, Vol. 605, Page 551-560, Year 2022 |
Publish date | May 27, 2021 (structure data deposition date) |
![]() | Cao, L. / Coventry, B. / Goreshnik, I. / Huang, B. / Sheffler, W. / Park, J.S. / Jude, K.M. / Markovic, I. / Kadam, R.U. / Verschueren, K.H.G. ...Cao, L. / Coventry, B. / Goreshnik, I. / Huang, B. / Sheffler, W. / Park, J.S. / Jude, K.M. / Markovic, I. / Kadam, R.U. / Verschueren, K.H.G. / Verstraete, K. / Walsh, S.T.R. / Bennett, N. / Phal, A. / Yang, A. / Kozodoy, L. / DeWitt, M. / Picton, L. / Miller, L. / Strauch, E.M. / DeBouver, N.D. / Pires, A. / Bera, A.K. / Halabiya, S. / Hammerson, B. / Yang, W. / Bernard, S. / Stewart, L. / Wilson, I.A. / Ruohola-Baker, H. / Schlessinger, J. / Lee, S. / Savvides, S.N. / Garcia, K.C. / Baker, D. |
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Methods | X-ray diffraction |
Resolution | 1.5 - 3.01 Å |
Structure data | ![]() PDB-7n1j: ![]() PDB-7n1k: ![]() PDB-7n3t: ![]() PDB-7opb: ![]() PDB-7rdh: ![]() PDB-7s5b: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-EDO: ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-PGE: ![]() ChemComp-PEG: |
Source |
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![]() | SIGNALING PROTEIN / Receptor tyrosine kinase / Complex / Binder / MEMBRANE PROTEIN / DE NOVO PROTEIN / PROTEIN BINDING / protein binder / IL7R / antagonist / VIRAL PROTEIN/DE NOVO PROTEIN / de novo design / mini protein / HA stem binder / VIRAL PROTEIN / VIRAL PROTEIN-DE NOVO PROTEIN complex / minibinder protein inhibitor cytokine receptor interleukin-7 |