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Structure paper

TitleStructural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 118, Year 2021
Publish dateJul 16, 2020 (structure data deposition date)
AuthorsCui, W. / Braun, E. / Wang, W. / Tang, J. / Zheng, Y. / Slater, B. / Li, N. / Chen, C. / Liu, Q. / Wang, B. ...Cui, W. / Braun, E. / Wang, W. / Tang, J. / Zheng, Y. / Slater, B. / Li, N. / Chen, C. / Liu, Q. / Wang, B. / Li, X. / Duan, Y. / Xiao, Y. / Ti, R. / Hotter, D. / Ji, X. / Zhang, L. / Cui, J. / Xiong, Y. / Sauter, D. / Wang, Z. / Kirchhoff, F. / Yang, H.
External linksProc. Natl. Acad. Sci. USA / PubMed:33876762
MethodsX-ray diffraction
Resolution2.284 - 3 Å
Structure data

PDB-7ckf:
The N-terminus of interferon-inducible antiviral protein-dimer
Method: X-RAY DIFFRACTION / Resolution: 2.284 Å

PDB-7e58:
interferon-inducible anti-viral protein 2
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-7e59:
interferon-inducible anti-viral protein truncated
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7e5a:
interferon-inducible anti-viral protein R356A
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-AF3:
ALUMINUM FLUORIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / antiviral / interferon-induced / GTPase / anti-HIV

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