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-Structure paper
Title | 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-beta-lactamases. |
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Journal, issue, pages | Chem Sci, Vol. 12, Page 2898-2908, Year 2021 |
Publish date | Aug 2, 2020 (structure data deposition date) |
![]() | Rossi, M.A. / Martinez, V. / Hinchliffe, P. / Mojica, M.F. / Castillo, V. / Moreno, D.M. / Smith, R. / Spellberg, B. / Drusano, G.L. / Banchio, C. ...Rossi, M.A. / Martinez, V. / Hinchliffe, P. / Mojica, M.F. / Castillo, V. / Moreno, D.M. / Smith, R. / Spellberg, B. / Drusano, G.L. / Banchio, C. / Bonomo, R.A. / Spencer, J. / Vila, A.J. / Mahler, G. |
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Methods | X-ray diffraction |
Resolution | 1.4 - 1.8700095823 Å |
Structure data | ![]() PDB-6zyn: ![]() PDB-6zyo: ![]() PDB-6zyp: ![]() PDB-6zyq: ![]() PDB-6zyr: ![]() PDB-6zys: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-QT2: ![]() ChemComp-FMT: ![]() ChemComp-HOH: ![]() ChemComp-QST: ![]() ChemComp-SO4: ![]() ChemComp-EDO: ![]() ChemComp-NA: ![]() ChemComp-ACT: |
Source |
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![]() | ANTIMICROBIAL PROTEIN / antibiotic resistance / lactamase / zinc / inhibitor / metallo-b-lactamase / antiboitic resistance |