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Structure paper

TitleStructural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Journal, issue, pagesSci Rep, Vol. 13, Page 6940-6940, Year 2023
Publish dateApr 27, 2018 (structure data deposition date)
AuthorsGhafoori, S.M. / Petersen, G.F. / Conrady, D.G. / Calhoun, B.M. / Stigliano, M.Z.Z. / Baydo, R.O. / Grice, R. / Abendroth, J. / Lorimer, D.D. / Edwards, T.E. / Forwood, J.K.
External linksSci Rep / PubMed:37117205
MethodsX-ray diffraction
Resolution1.95 - 2.95 Å
Structure data

PDB-6d8w:
Crystal structure of InvbI.18715.a.KN11: Influenza hemagglutinin from strain A/Jiangsu/ALSI/2011
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-6ml8:
Crystal structure of hemagglutinin from H1N1 Influenza A virus A/Denver/57 bound to the C05 antibody
Method: X-RAY DIFFRACTION / Resolution: 2.92 Å

PDB-6mya:
Crystal structure of InvbP.18715.a.KN11: Influenza hemagglutinin from strain A/Almaty/32/1998
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-6n41:
Crystal structure of InvbM.18715.a.KN11: Influenza hemagglutinin from strain A/Netherlands/002P1/1951
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6ona:
Crystal structure of Influenza hemagglutinin from strain A/Hickox/JY2/1940
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-6osr:
Crystal structure of Influenza hemagglutinin from strain A/Melbourne/1/1946(H1N1)
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-7jp4:
Crystal structure of a refolded head domain hemagglutinin HA from Influenza A virus A/Fort Monmouth/1/1947
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7jpd:
Crystal structure of the trimeric full length mature hemagglutinin from influenza A virus A/Fort Monmouth/1/1947
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-OXM:
OXAMIC ACID

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CL:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-MPO:
3[N-MORPHOLINO]PROPANE SULFONIC ACID / pH buffer*YM

ChemComp-IOD:
IODIDE ION

Source
  • influenza a virus
  • influenza a virus (a/denver/1957(h1n1))
  • homo sapiens (human)
  • influenza a virus (strain a/hickox/1940 h1n1)
  • influenza a virus (a/melbourne/1/1946(h1n1))
  • influenza a virus (a/fort monmouth/1/1947(h1n1))
KeywordsVIRAL PROTEIN / Inflenza hemagglutinin / Structural Genomics / STRIVE / SSGCID / Seattle Structural Genomics Center for Infectious Disease / NIAID / influenza virus / vaccine development / broadly neutralizing antibody / strain-specific neutralization / influenzavirus / National Institute of Allergy and Infectious Disease / flu / vaccine / seasonal flu / refolded protein / head domain / National Institutes of Allergy and Infectious Diseases / HA / antigen

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