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TitleMultimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-gamma 1 Protein.
Journal, issue, pagesBiochemistry, Vol. 56, Page 2225-2237, Year 2017
Publish dateOct 14, 2016 (structure data deposition date)
AuthorsMcKercher, M.A. / Guan, X. / Tan, Z. / Wuttke, D.S.
External linksBiochemistry / PubMed:28376302
MethodsX-ray diffraction
Resolution1.4 - 1.876 Å
Structure data

PDB-5tnw:
Phospholipase C gamma-1 C-terminal SH2 domain
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-5to4:
Phospholipase C gamma-1 C-terminal SH2 domain, spacegroup P212121
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-5tq1:
Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the insulin receptor
Method: X-RAY DIFFRACTION / Resolution: 1.485 Å

PDB-5tqs:
Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2
Method: X-RAY DIFFRACTION / Resolution: 1.876 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • bos taurus (cattle)
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsHYDROLASE / SH2 / Phospholipase / phosphopeptide

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