+Search query
-Structure paper
Title | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. |
---|---|
Journal, issue, pages | J. Mol. Biol., Vol. 409, Page 504-512, Year 2011 |
Publish date | Sep 3, 2009 (structure data deposition date) |
Authors | Cendron, L. / Ramazzina, I. / Percudani, R. / Rasore, C. / Zanotti, G. / Berni, R. |
External links | J. Mol. Biol. / PubMed:21515285 |
Methods | X-ray diffraction |
Resolution | 1.68 - 2.3 Å |
Structure data | PDB-3iwu: PDB-3iwv: PDB-3q1e: |
Chemicals | ChemComp-HOH: ChemComp-T44: |
Source |
|
Keywords | HYDROLASE / HIUase / Transthyretin / TRP / thyroid hormones / molecular evolution / Peroxisome / Purine metabolism / uric acid degradation / Greek key beta-barrel / Point Mutation |