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Structure paper

TitleEctopic NMDAR expression in cancer unmasks germline-encoded autoimmunity
Journal, issue, pagesTo Be Published
Publish dateJan 15, 2026 (structure data deposition date)
AuthorsKleeman SO / Furukawa HF
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.09 - 4.55 Å
Structure data

75112

10en

EMDB-75112, PDB-10en:
SK3D-Matured in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 3.7 Å

75120

10ev

EMDB-75120, PDB-10ev:
OX1-Matured in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.2 Å

75121

10ex

EMDB-75121, PDB-10ex:
SK5A-Matured apo state in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.08 Å

75122

10ey

EMDB-75122, PDB-10ey:
SK5B-Matured in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.1 Å

75123

10ez

EMDB-75123, PDB-10ez:
SK3D-Germline in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 3.76 Å

75127

10fd

EMDB-75127, PDB-10fd:
SK5G-Matured in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 3.09 Å

75128

10fe

EMDB-75128, PDB-10fe:
OX1-Germline in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.55 Å

75129

10ff

EMDB-75129, PDB-10ff:
SK5A-Matured glycine/glutamate in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.06 Å

75134

10fl

EMDB-75134, PDB-10fl:
SK5G-Germline
Method: EM (single particle) / Resolution: 3.81 Å

75136

10fn

EMDB-75136, PDB-10fn:
SK5A-Germline in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.52 Å

75138

10fo

EMDB-75138, PDB-10fo:
SK5B-Germline in complex with GluN1-GluN2B, full refinement
Method: EM (single particle) / Resolution: 4.46 Å

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN/Immune System / NMDAR / antibody / SIGNALING PROTEIN / SIGNALING PROTEIN-Immune System complex / SIGNALING PROTEIN/Imuune System / SIGNALING PROTEIN-Imuune System complex

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