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Structure paper

TitleStructural basis of TACO1-mediated efficient mitochondrial translation
Journal, issue, pagesNat Commun, Year 2026
Publish dateJul 7, 2025 (structure data deposition date)
AuthorsWang S / Brischigliaro M / Zhang Y / Wu C / Zheng W / Barrientos A / Xiong Y
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution2.9 - 3.18 Å
Structure data

71623

9pg8

EMDB-71623, PDB-9pg8:
In situ structure of the human mitoribosome in the P-E state
Method: EM (single particle) / Resolution: 3.06 Å

71630

9pgf

EMDB-71630, PDB-9pgf:
In situ structure of the human mitoribosome in the P state
Method: EM (single particle) / Resolution: 2.93 Å

71633

9pgi

EMDB-71633, PDB-9pgi:
In situ structure of the human mitoribosome in the A-P-E state with TACO1
Method: EM (single particle) / Resolution: 3.02 Å

71634

9pgl

EMDB-71634, PDB-9pgl:
In situ structure of the human mitoribosome in the A-P state with TACO1
Method: EM (single particle) / Resolution: 2.9 Å

71635

9pgm

EMDB-71635, PDB-9pgm:
In situ structure of the human mitoribosome in the P-E state from TACO1-knockout cells
Method: EM (single particle) / Resolution: 3.18 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-SPD:
SPERMIDINE

ChemComp-PUT:
1,4-DIAMINOBUTANE

ChemComp-MG:
Unknown entry

ChemComp-VAL:
VALINE

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-SPM:
SPERMINE

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsRIBOSOME / mitochondria / mitoribosome / inner membrane

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