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-Structure paper
Title | Nucleic acid mediated activation of prokaryotic Argonaute immune system |
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Journal, issue, pages | Nat Commun, Year 2024 |
Publish date | Sep 13, 2023 (structure data deposition date) |
Authors | Kottur J / Malik R / Aggarwal AK |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 3.15 - 3.37 Å |
Structure data | EMDB-41945: Locally refined (symmetry based) cryo-EM map of the dimer of the SPARTA oligomer with guide RNA and target DNA EMDB-41947: Locally refined (symmetry based) cryo-EM map of the second dimer of the SPARTA oligomer with guide RNA and target DNA EMDB-41948: Focused refined cryo-EM map of the TIR domains of the SPARTA oligomer EMDB-41959: Original Cryo-EM map of the SPARTA oligomer with guide RNA and target DNA EMDB-41966, PDB-8u72: |
Chemicals | ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | RNA BINDING PROTEIN/RNA/DNA / RNA / DNA / Argonaute / TIR / immune system / RNA BINDING PROTEIN-RNA-DNA complex |