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Title | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1 |
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Journal, issue, pages | Nat Commun, Year 2024 |
Publish date | Oct 30, 2023 (structure data deposition date) |
Authors | Tamura T / Ito J / Uriu K / Zahradnik J / Kida I / Anraku Y / Nasser H / Shofa M / Oda Y / Lytras S ...Tamura T / Ito J / Uriu K / Zahradnik J / Kida I / Anraku Y / Nasser H / Shofa M / Oda Y / Lytras S / Nao N / Itakura Y / Deguchi S / Suzuki R / Wang L / Begum MM / Kita S / Yajima H / Sasaki J / Sasaki-Tabata K / Shimizu R / Tsuda M / Kosugi Y / Fujita S / Pan L / Sauter D / Yoshimatsu K / Suzuki S / Asakura H / Nagashima M / Sadamasu K / Yoshimura K / Yamamoto Y / Nagamoto T / Schreiber G / Maenaka K / Hashiguchi T / Ikeda T / Fukuhara T / Saito A / Tanaka S / Matsuno K / Takayama K / Sato K |
External links | Nat Commun / Search PubMed |
Methods | EM (single particle) |
Resolution | 2.59 - 4.3 Å |
Structure data | EMDB-37910, PDB-8wxl: EMDB-38459, PDB-8xux: EMDB-38686, PDB-8xuy: EMDB-38687, PDB-8xuz: EMDB-38688, PDB-8xv0: EMDB-38689, PDB-8xv1: EMDB-38690, PDB-8xvm: EMDB-60886, PDB-9iu1: EMDB-60904: Structure of SARS-CoV-2 JN.1 spike glycoprotein in complex with ACE2 (2-up state) EMDB-60905: Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (1 highly-open RBD and 1 partially-open RBD) EMDB-60906: Structure of SARS-CoV-2 JN.1 spike glycoprotein in complex with ACE2 (2-up and 1-down state) |
Chemicals | ChemComp-NAG: |
Source |
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Keywords | VIRAL PROTEIN / spike protein / glycoprotein / VIRUS / VIRAL PROTEIN/PROTEIN BINDING / VIRAL PROTEIN-PROTEIN BINDING complex |