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Title | Cryo-EM structure of human 26S proteasomal RP subcomplex bound with branched Ub chain. |
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Journal, issue, pages | To Be Published |
Publish date | Jun 16, 2023 (structure data deposition date) |
![]() | Draczkowski P / Hsu STD / Wang YS |
![]() | Search PubMed |
Methods | EM (single particle) |
Resolution | 3.4 - 4.0 Å |
Structure data | EMDB-36598, PDB-8jri: EMDB-36605, PDB-8jrt: EMDB-36645, PDB-8jti: EMDB-36764, PDB-8k0g: ![]() EMDB-37269: Consensus cryo-EM structure of human 26S proteasomal RP subcomplex (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub. ![]() EMDB-37273: Local refinement cryo-EM map of human 26S RP (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub, focused on the Ub binding region. ![]() EMDB-37276: Local refinement cryo-EM map of human 26S RP (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub, focused on Rpn3/Rpn7 region. ![]() EMDB-37277: Local refinement cryo-EM map of human 26S RP (Ea state) bound to K11/K48-branched ubiquitin (Ub) chain composed of three Ub, focused on AAA+ ATPase subcomplex. ![]() EMDB-37317: Consensus cryo-EM map of human 26S RP (Eb state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub. ![]() EMDB-37319: Local refinement cryo-EM map of human 26S RP (Eb state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on the Ub binding region. ![]() EMDB-37327: Local refinement cryo-EM map of human 26S RP (Eb state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on Rpn3/Rpn7 region. ![]() EMDB-37328: Local refinement cryo-EM map of human 26S RP (Eb state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on AAA+ ATPase subcomplex. ![]() EMDB-37334: Consensus cryo-EM map of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub. ![]() EMDB-37335: Local refinement cryo-EM map of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on the Ub binding region. ![]() EMDB-37341: Local refinement cryo-EM map of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on the RP lid. ![]() EMDB-37344: Local refinement cryo-EM map of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub, focused on AAA+ ATPase subcomplex. |
Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-MG: ![]() ChemComp-ADP: |
Source |
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![]() | CYTOSOLIC PROTEIN / protein degradation / macromolecular complex / ubiquitin-proteasome system |