Title | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Year 2024 |
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Publish date | Jul 26, 2022 (structure data deposition date) |
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Authors | Qian L / Jun Z / Xiang Z / Wang Z / Tong C / Duo J / Zhenguo C / Wang L |
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External links | Nat. Struct. Mol. Biol. / Search PubMed |
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Methods | EM (single particle) |
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Resolution | 3.2 - 8.5 Å |
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Structure data | EMDB-33914, PDB-7ylm: Cryo-EM structure of 8-subunit Smc5/6 hinge region Method: EM (single particle) / Resolution: 6.17 Å EMDB-34025, PDB-7yqh: Cryo-EM structure of 8-subunit Smc5/6 Method: EM (single particle) / Resolution: 5.6 Å EMDB-34953, PDB-8hqs: Cryo-EM structure of 8-subunit Smc5/6 head region Method: EM (single particle) / Resolution: 3.2 Å EMDB-35116, PDB-8i13: Cryo-EM structure of 6-subunit Smc5/6 Method: EM (single particle) / Resolution: 6.9 Å EMDB-35128, PDB-8i21: Cryo-EM structure of 6-subunit Smc5/6 arm region Method: EM (single particle) / Resolution: 6.02 Å EMDB-35184, PDB-8i4u: Cryo-EM structure of 5-subunit Smc5/6 hinge region Method: EM (single particle) / Resolution: 6.73 Å EMDB-35185, PDB-8i4v: Cryo-EM structure of 5-subunit Smc5/6 arm region Method: EM (single particle) / Resolution: 5.97 Å EMDB-35186, PDB-8i4w: Cryo-EM structure of 5-subunit Smc5/6 head region Method: EM (single particle) / Resolution: 6.01 Å EMDB-35187, PDB-8i4x: Cryo-EM structure of 5-subunit Smc5/6 Method: EM (single particle) / Resolution: 8.5 Å EMDB-37584, PDB-8wjl: Cryo-EM structure of 6-subunit Smc5/6 hinge region Method: EM (single particle) / Resolution: 6.15 Å EMDB-37586, PDB-8wjn: Cryo-EM structure of 6-subunit Smc5/6 head region Method: EM (single particle) / Resolution: 5.58 Å EMDB-37587, PDB-8wjo: Cryo-EM structure of 8-subunit Smc5/6 arm region Method: EM (single particle) / Resolution: 6.04 Å EMDB-60245: Smc5/6-5mer consensus map Method: EM (single particle) / Resolution: 8.5 Å EMDB-60246: Smc5/6-6mer consensus map Method: EM (single particle) / Resolution: 6.9 Å |
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Source | ![](img/tx_yeast.gif) saccharomyces cerevisiae (brewer's yeast)![](img/tx_yeast.gif) saccharomyces cerevisiae s288c (yeast)
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Keywords | CELL CYCLE |
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