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TitleStructural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Journal, issue, pagesBiopolym Cell, Year 2023
Publish dateAug 7, 2023 (structure data deposition date)
AuthorsKolosova O / Zgadzay Y / Stetsenko A / Atamas A / Wu C / Jenner L / Sachs SM / Guskov A / Yusupov M
External linksBiopolym Cell / Search PubMed
MethodsEM (single particle)
Resolution2.45 - 3.0 Å
Structure data

EMDB-18150: Cryo-EM map of the Candida albicans 80S ribosome in complex with cephaeline
Method: EM (single particle) / Resolution: 2.45 Å

EMDB-18151: Focused map on the body of the SSU of the Candida albicans 80S ribosome in complex with cephaeline
Method: EM (single particle) / Resolution: 2.9 Å

EMDB-18155: The cryo-EM map of the C. albicans ribosome focused on the head of the SSU
Method: EM (single particle) / Resolution: 3.0 Å

18156

8q5i

EMDB-18156: Combined map of Candida albicans 80S ribosome in complex with cephaeline
PDB-8q5i: Structure of Candida albicans 80S ribosome in complex with cephaeline
Method: EM (single particle) / Resolution: 2.45 Å

Chemicals

ChemComp-SPK:
SPERMINE (FULLY PROTONATED FORM)

ChemComp-K16:
Cephaeline / alkaloid*YM

ChemComp-SPD:
SPERMIDINE

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • candida albicans (yeast)
  • synthetic construct (others)
KeywordsRIBOSOME / Candida albicans / cephaeline

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