タイトル | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. |
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ジャーナル・号・ページ | Nat. Med., Vol. 26, Page 1135-1145, Year 2020 |
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掲載日 | 2019年2月22日 (構造データの登録日) |
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著者 | Murugan, R. / Scally, S.W. / Costa, G. / Mustafa, G. / Thai, E. / Decker, T. / Bosch, A. / Prieto, K. / Levashina, E.A. / Julien, J.P. / Wardemann, H. |
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リンク | Nat. Med. / PubMed:32451496 |
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手法 | X線回折 |
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解像度 | 1.4 - 2.9 Å |
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構造データ | PDB-6o23: Crystal structure of 2243 Fab in complex with circumsporozoite protein NANP5 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-6o24: Crystal structure of 4498 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-6o25: Crystal structure of 3945 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-6o26: Crystal structure of 3246 Fab in complex with circumsporozoite protein NANA 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-6o28: Crystal structure of 4493 Fab in complex with circumsporozoite protein KQPA and anti-kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-6o29: Crystal structure of 4493 Fab in complex with circumsporozoite protein NPDP and anti-kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-6o2a: Crystal structure of 4493 Fab in complex with circumsporozoite protein NDN and anti-kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-6o2b: Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-6o2c: Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 2.017 Å PDB-6ule: Crystal structure of 2541 Fab in complex with circumsporozoite protein NANP5 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-6ulf: Crystal structure of 4498 Fab in complex with circumsporozoite protein NDN3 and anti-Kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-6vln: Crystal structure of 4498 Fab in complex with circumsporozoite protein DND3 and anti-Kappa VHH domain 手法: X-RAY DIFFRACTION / 解像度: 1.63 Å |
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化合物 | |
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由来 | - homo sapiens (ヒト)
- plasmodium falciparum (マラリア病原虫)
- lama glama (ラマ)
- camelidae mixed library (哺乳類)
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キーワード | IMMUNE SYSTEM / Malaria / antibody |
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