EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
ジャーナル・号・ページ	Cell(Cambridge,Mass. ), Vol. 161, Page 1280-1292, Year 2015
掲載日	2014年12月8日 (構造データの登録日)
著者	Zhou, T. / Lynch, R.M. / Chen, L. / Acharya, P. / Wu, X. / Doria-Rose, N.A. / Joyce, M.G. / Lingwood, D. / Soto, C. / Bailer, R.T. ...Zhou, T. / Lynch, R.M. / Chen, L. / Acharya, P. / Wu, X. / Doria-Rose, N.A. / Joyce, M.G. / Lingwood, D. / Soto, C. / Bailer, R.T. / Ernandes, M.J. / Kong, R. / Longo, N.S. / Louder, M.K. / McKee, K. / O'Dell, S. / Schmidt, S.D. / Tran, L. / Yang, Z. / Druz, A. / Luongo, T.S. / Moquin, S. / Srivatsan, S. / Yang, Y. / Zhang, B. / Zheng, A. / Pancera, M. / Kirys, T. / Georgiev, I.S. / Gindin, T. / Peng, H.P. / Yang, A.S. / Mullikin, J.C. / Gray, M.D. / Stamatatos, L. / Burton, D.R. / Koff, W.C. / Cohen, M.S. / Haynes, B.F. / Casazza, J.P. / Connors, M. / Corti, D. / Lanzavecchia, A. / Sattentau, Q.J. / Weiss, R.A. / West, A.P. / Bjorkman, P.J. / Scheid, J.F. / Nussenzweig, M.C. / Shapiro, L. / Mascola, J.R. / Kwong, P.D.
リンク	Cell(Cambridge,Mass. ) / PubMed:26004070
手法	X線回折
解像度	1.8 - 3.452 Å
構造データ	PDB-4rwy: Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 手法: X-RAY DIFFRACTION / 解像度: 2.128 Å PDB-4rx4: Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120 手法: X-RAY DIFFRACTION / 解像度: 3.45 Å PDB-4ydi: Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17 手法: X-RAY DIFFRACTION / 解像度: 3.452 Å PDB-4ydj: Crystal structure of broadly and potently neutralizing antibody 44-VRC13.01 in complex with HIV-1 clade AE strain 93TH057 gp120 手法: X-RAY DIFFRACTION / 解像度: 2.308 Å PDB-4ydk: Crystal structure of broadly and potently neutralizing antibody C38-VRC16.01 in complex with HIV-1 clade AE strain 93TH057 gp120 手法: X-RAY DIFFRACTION / 解像度: 2.051 Å PDB-4ydl: Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-4ye4: Crystal Structure of Neutralizing Antibody HJ16 in Complex with HIV-1 gp120 手法: X-RAY DIFFRACTION / 解像度: 2.72 Å PDB-4yfl: Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120 手法: X-RAY DIFFRACTION / 解像度: 3.387 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤YM ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-HOH: WATER ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-IPA: ISOPROPYL ALCOHOL / 2-プロパノ-ル / alkaloidYM ChemComp-BU3: (R,R)-2,3-BUTANEDIOL / (2R,3R)-2,3-ブタンジオ-ル ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-CL: Unknown entry / クロリド ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-NHE: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / 2-(シクロヘキシルアミノ)エタンスルホン酸 / pH緩衝剤*YM
由来	human immunodeficiency virus 1 (ヒト免疫不全ウイルス) homo sapiens (ヒト) human immunodeficiency virus (ヒト免疫不全ウイルス)
キーワード	VIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 attachment protein / Broadly neutralizing antibody 8ANC131 / VIRAL PROTEIN-IMMUNE SYSTEM complex / Broadly neutralizing antibody / IMMUNE SYSTEM / Antibody / HIV-1 / HIV1 / gp120 / complex / HIV-1 CD4 binding site