EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase.
ジャーナル・号・ページ	J. Biol. Chem., Vol. 288, Page 26201-26208, Year 2013
掲載日	2011年12月8日 (構造データの登録日)
著者	Jrgensen, R. / Pesnot, T. / Lee, H.J. / Palcic, M.M. / Wagner, G.K.
リンク	J. Biol. Chem. / PubMed:23836908
手法	X線回折
解像度	1.65 - 1.9 Å
構造データ	PDB-3v0l: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (2GW) 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-3v0m: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (5GW) and H-antigen acceptor 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-3v0n: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (3GW and 4GW) 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-3v0o: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (4GW) and H-antigen acceptor 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-3v0p: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (4GW) and H-antigen acceptor 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3v0q: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP and H-antigen acceptor 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å
化合物	ChemComp-MN: Unknown entry ChemComp-2GW: 5-phenyl-uridine-5'-alpha-d-galactosyl-diphosphate / ヒドロキシ(5-フェニル-5′-ウリジリルオキシ)ホスフィニルα-D-ガラクトピラノシド ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-HOH: WATER ChemComp-5GW: 5-phenyluridine 5'-(trihydrogen diphosphate) ChemComp-BHE: octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside / オクチル2-O-(α-L-フコピラノシル)-β-D-ガラクトピラノシド ChemComp-4GW: 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate) ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-3GW: 5-(5-formylthiophen-2-yl)uridine-5'(2-(acetylamino)-2-deoxy-alpha-D-galactosyl)-diphosphate ChemComp-UDP: URIDINE-5'-DIPHOSPHATE / UDP / UDP*YM
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE/TRANSFERASE INHIBITOR / GTA / ABO / CISAB MUTANT / ROSSMANN FOLD / "Semi-closed" CONFORMATION / GLYCOSYLTRANSFERASE / GLYCOPROTEIN / BLOOD GROUP ANTIGEN / UDP-GalNAc / METAL-BINDING / MANGANESE / Glycosylation / TRANSMEMBRANE / GOLGI APPARATUS / SECRETED / SIGNAL-ANCHOR / TRANSFERASE-TRANSFERASE INHIBITOR complex / AA(GLY)B / "closed" CONFORMATION / TRANSFERASE