EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor
ジャーナル・号・ページ	Plos One, Vol. 8, Page e64240-e64240, Year 2013
掲載日	2006年11月1日 (構造データの登録日)
著者	Biela, I. / Tidten-Luksch, N. / Immekus, F. / Glinca, S. / Nguyen, T.X. / Gerber, H.D. / Heine, A. / Klebe, G. / Reuter, K.
リンク	Plos One / PubMed:23704982
手法	X線回折
解像度	1.18 - 2.25 Å
構造データ	PDB-2nqz: Trna-guanine transglycosylase (TGT) mutant in complex with 7-deaza-7-aminomethyl-guanine 手法: X-RAY DIFFRACTION / 解像度: 1.46 Å PDB-2nso: Trna-gunanine-transglycosylase (TGT) mutant Y106F, C158V, A232S, V233G- APO-Structure 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3bl3: tRNA guanine transglycosylase V233G mutant apo structure 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-3bld: tRNA guanine transglycosylase V233G mutant preQ1 complex structure 手法: X-RAY DIFFRACTION / 解像度: 1.19 Å PDB-3bll: TGT mutant in complex with Boc-preQ1 手法: X-RAY DIFFRACTION / 解像度: 1.26 Å PDB-3blo: TGT mutant in complex with queuine 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-4e2v: tRNA-guanine transglycosylase Y106F, C158V mutant in complex with preQ1 手法: X-RAY DIFFRACTION / 解像度: 1.18 Å PDB-4gcx: tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with preQ1 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-4gd0: tRNA-guanine transglycosylase Y106F, C158V mutant 手法: X-RAY DIFFRACTION / 解像度: 1.29 Å PDB-4h6e: tRNA-guanine transglycosylase Y106F, C158V, V233G mutant apo structure 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-4h7z: tRNA-guanine transglycosylase Y106F, C158V mutant in complex with guanine 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-4hqv: tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with queuine 手法: X-RAY DIFFRACTION / 解像度: 1.66 Å PDB-4hsh: tRNA-guanine transglycosylase Y106F, V233G mutant in complex with queuine 手法: X-RAY DIFFRACTION / 解像度: 1.56 Å PDB-4hvx: tRNA-guanine transglycosylase Y106F, C158V mutant in complex with queuine 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-PRF: 7-DEAZA-7-AMINOMETHYL-GUANINE / 2-アミノ-5-(アミノメチル)-7H-ピロロ[2,3-d]ピリミジン-4(3H)-オン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-HOH: WATER ChemComp-BPQ: tert-butyl [(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]carbamate ChemComp-QEI: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one / ケウイン ChemComp-GUN: GUANINE / グアニン
由来	zymomonas mobilis (バクテリア) zymomonas mobilis subsp. mobilis (バクテリア)
キーワード	TRANSFERASE / TGT / preQ1 / TRNA-GUNANINE-TRANSGLYCOSYLASE (TGT) / TGT mutant / eukaryotic bindig pocket model system / Glycosyltransferase / Metal-binding / Queuosine biosynthesis / tRNA processing / Boc-preQ1 / queuine / transferase/transferase inhibitor / substrate specificity / bacterial TGT / guanin / tRNA / guanine exchange enzyme / transferase-transferase inhibitor complex / substrate specifity / guanine