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Structure paper

TitleA structural classification of the variant surface glycoproteins of the African trypanosomey.
Journal, issue, pagesPlos Negl Trop Dis, Vol. 17, Page e0011621-e0011621, Year 2023
Publish dateMar 27, 2023 (structure data deposition date)
AuthorsDakovic, S. / Zeelen, J.P. / Gkeka, A. / Chandra, M. / van Straaten, M. / Foti, K. / Zhong, J. / Vlachou, E.P. / Aresta-Branco, F. / Verdi, J.P. ...Dakovic, S. / Zeelen, J.P. / Gkeka, A. / Chandra, M. / van Straaten, M. / Foti, K. / Zhong, J. / Vlachou, E.P. / Aresta-Branco, F. / Verdi, J.P. / Papavasiliou, F.N. / Stebbins, C.E.
External linksPlos Negl Trop Dis / PubMed:37656766
MethodsX-ray diffraction
Resolution1.23 - 3.22 Å
Structure data

PDB-8ok4:
Variant Surface Glycoprotein VSG11wt-Oil
Method: X-RAY DIFFRACTION / Resolution: 1.23 Å

PDB-8ok5:
Variant Surface Glycoprotein VSG11 monomer with iodine
Method: X-RAY DIFFRACTION / Resolution: 1.27 Å

PDB-8ok6:
Variant Surface Glycoprotein VSG11 two monomers
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-8ok7:
Variant Surface Glycoprotein VSG558 NTD
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

PDB-8ok8:
Variant Surface Glycoprotein VSG615
Method: X-RAY DIFFRACTION / Resolution: 3.22 Å

PDB-8onh:
Variant Surface Glycoprotein VSG11wt-Oil
Method: X-RAY DIFFRACTION / Resolution: 2.59 Å

PDB-8q0e:
Crystal Structure of the N-terminal Domain of Variant Surface Glycoprotein 545 (VSG545) of Trypanosome brucei brucei Lister 427
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-8q0p:
Crystal Structure of an N-terminal Domain of Variant Surface Glycoprotein 21 (VSG21) of Trypanosome brucei brucei Lister 427
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-IOD:
IODIDE ION

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • trypanosoma brucei brucei (eukaryote)
KeywordsMEMBRANE PROTEIN / Variant surface glycoprotein Suramin Trypanosomiasis Drug resistance Glycosylation / Variant surface glycoprotein / Trypanosomiasis / Glycosylation / Variant surface glycoprotein Suramin Trypanosomiasis Glycosylation MEMBRANE PROTEIN

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