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-Structure paper
Title | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. |
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Journal, issue, pages | Nat Commun, Vol. 13, Page 5470-5470, Year 2022 |
Publish date | Feb 2, 2022 (structure data deposition date) |
Authors | Jiang, J. / Taylor, D.K. / Kim, E.J. / Boyd, L.F. / Ahmad, J. / Mage, M.G. / Truong, H.V. / Woodward, C.H. / Sgourakis, N.G. / Cresswell, P. ...Jiang, J. / Taylor, D.K. / Kim, E.J. / Boyd, L.F. / Ahmad, J. / Mage, M.G. / Truong, H.V. / Woodward, C.H. / Sgourakis, N.G. / Cresswell, P. / Margulies, D.H. / Natarajan, K. |
External links | Nat Commun / PubMed:36115831 |
Methods | X-ray diffraction |
Resolution | 1.25 - 3.9 Å |
Structure data | PDB-7tuc: PDB-7tud: PDB-7tue: PDB-7tuf: PDB-7tug: PDB-7tuh: |
Chemicals | ChemComp-GOL: ChemComp-EDO: ChemComp-HOH: ChemComp-NAG: |
Source |
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Keywords | IMMUNE SYSTEM / tapasin / histocompatibility complex class I / MHC-I / HLA / peptide editing / peptide loading complex / PLC / antigen presentation / immune response / PaSta / Fab / Antibody / IgG |