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Structure paper

TitleMolecular determinants for substrate uptake in electrogenic sodium/proton antiporters
Journal, issue, pagesTo Be Published
Publish dateAug 11, 2020 (structure data deposition date)
AuthorsFippel, A. / Mir, S.H. / Wirth, C. / Gross, N.M. / Lentes, C.J. / Bialas, E. / Frank, F. / Ulbrich, M.H. / Andrade, S.L.A. / Kulik, A. / Hunte, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.04 - 2.45 Å
Structure data

PDB-7a0w:
Structure of dimeric sodium proton antiporter NhaA, at pH 8.5, crystallized with chimeric Fab antibodies
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

PDB-7a0x:
Structure of dimeric sodium proton antiporter NhaA, at pH 6.0, crystallized with chimeric Fab antibodies
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

PDB-7a0y:
Structure of dimeric sodium proton antiporter NhaA K300R variant, at pH 8.2, crystallized with chimeric Fab antibodies
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-CDL:
CARDIOLIPIN / phospholipid*YM

ChemComp-3PH:
1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-3PE:
1,2-Distearoyl-sn-glycerophosphoethanolamine / phospholipid*YM

ChemComp-CA:
Unknown entry

Source
  • salmonella enterica subsp. enterica serovar typhimurium str. lt2 (bacteria)
  • gallus gallus (chicken)
  • homo sapiens (human)
  • salmonella typhimurium (strain lt2 / sgsc1412 / atcc 700720) (bacteria)
KeywordsMEMBRANE PROTEIN / sodium proton antiporter / transporter / antibody / chimeric Fab

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