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TitleMatters arising: There is no structure of the catalytic intermediate of GTP-mediated mRNA capping by the SARS-CoV-2 NiRAN domain, and thus the mechanism remains unknown
Journal, issue, pagesTo Be Published
Publish dateSep 6, 2024 (structure data deposition date)
AuthorsSmall GI / Darst SA / Campbell EA
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.58 Å
Structure data

46936

9dj8

EMDB-46936, PDB-9dj8:
RNA-nsp9 bound to the NiRAN domain of the E-RTC with an empty G-pocket
Method: EM (single particle) / Resolution: 2.58 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / RdRp / nsp9 / NiRAN / RNA-nsp9 / nsp12 / RTC

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