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Structure paper

TitleMycobacterial EtfD contains an unusual linear [3Fe-4S] cluster and enables beta oxidation to drive proton pumping by the electron transport chain
Journal, issue, pagesTo Be Published
Publish dateMay 8, 2025 (structure data deposition date)
AuthorsCourbon GM / Rubinstein JL
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.8 - 3.2 Å
Structure data

70545

9ojn

EMDB-70545, PDB-9ojn:
Structure of Mycobacterium smegmatis EtfD
Method: EM (single particle) / Resolution: 3.2 Å

EMDB-70546: CryoEM map of Mycobacterium smegmatis EtfD cytosolic region
Method: EM (single particle) / Resolution: 2.8 Å

Chemicals

ChemComp-LMT:
DODECYL-BETA-D-MALTOSIDE / detergent*YM

ChemComp-MQ9:
MENAQUINONE-9

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-9S8:
Non-cubane [4Fe-4S]-cluster

PDB-1cbx:
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND THE BIPRODUCT ANALOG INHIBITOR L-BENZYLSUCCINATE AT 2.0 ANGSTROMS RESOLUTION

Source
  • mycolicibacterium smegmatis mc2 155 (bacteria)
KeywordsOXIDOREDUCTASE / membrane protein / electron transport chain / beta oxidation

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