Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	A planar dimer of bovine ATP synthase.
Journal, issue, pages	Cell Death Differ, Year 2026
Publish date	Jul 3, 2026
Authors	Chimari Jiko / Atsuki Nakano / Yosuke Teshirogi / Eiki Yamashita / Genji Kurisu / Daron Standley / Tohru Terada / Kaoru Mitsuoka / Ken Yokoyama / Christoph Gerle /
PubMed Abstract	Mammalian mitochondrial ATP synthase typically organizes into rows of V-shaped dimers that impose significant membrane curvature essential for mitochondrial cristae formation. Using gentle, column- ...Mammalian mitochondrial ATP synthase typically organizes into rows of V-shaped dimers that impose significant membrane curvature essential for mitochondrial cristae formation. Using gentle, column-free purification combined with single-particle cryo-electron microscopy, we have identified a previously unrecognized planar dimeric form of bovine ATP synthase exhibiting minimal membrane bending. This planar dimer is characterized structurally by anti-parallel arrangement of two ATP synthase complexes linked by a straight conformation of inhibitory factor 1 (IF1), a sharp contrast to the kinked IF1 observed in tetrameric assemblies. Molecular dynamics simulations confirm that transitioning between straight and kinked IF1 conformations occurs without significant energetic barriers. The planar dimer also displays distinct peripheral stalk positioning relative to its adjacent α subunit. These structural divergences suggest a specialized function and a distinct localization for planar ATP synthase dimers, providing structural support for a division of labor within mitochondrial ATP synthase populations.
External links	Cell Death Differ / PubMed:42399642
Methods	EM (single particle)
Resolution	2.2 - 7.9 Å
Structure data	65237 9vpb EMDB-65237: IF1 bound bovine F-ATP synthase planar dimer PDB-9vpb: Cryo-EM structure of the IF1 bound bovine F-ATP synthase planar dimer Method: EM (single particle) / Resolution: 5.0 Å 65238 9vpc EMDB-65238: IF1 bound bovine ATP synthase tetramer, C2 symmetry imposed PDB-9vpc: Cryo-EM structure of the IF1 bound bovine ATP synthase tetramer Method: EM (single particle) / Resolution: 7.2 Å 65239 9vpd EMDB-65239: IF1 bound bovine ATP synthase monomer: rotary state 1, F1 focused map PDB-9vpd: Cryo-EM structure of the IF1 bound bovine ATP synthase monomer: rotary state 1, F1 focused map Method: EM (single particle) / Resolution: 2.3 Å EMDB-65240: IF1 bound bovine ATP synthase tetramer, no symmetry imposed Method: EM (single particle) / Resolution: 7.9 Å EMDB-65241: IF1 bound bovine ATP synthase tetramer: Fo focused map of the state 1 protomer of dimer B Method: EM (single particle) / Resolution: 4.0 Å EMDB-65242: IF1 bound bovine ATP synthase monomer, rotary state 2 Method: EM (single particle) / Resolution: 2.6 Å EMDB-65243: IF1 bound bovine ATP synthase monomer, rotary state 2, F1 focused map Method: EM (single particle) / Resolution: 2.6 Å EMDB-65244: IF1 bound bovine ATP synthase monomer: rotary state 2, Fo focused map Method: EM (single particle) / Resolution: 3.6 Å EMDB-65245: IF1 bound bovine ATP synthase monomer: rotary state 3 Method: EM (single particle) / Resolution: 2.4 Å EMDB-65246: IF1 bound bovine ATP synthase monomer: rotary state 3, F1 focused map Method: EM (single particle) / Resolution: 2.2 Å EMDB-65247: IF1 bound bovine ATP synthase monomer: rotary state 3, Fo focused map Method: EM (single particle) / Resolution: 3.3 Å EMDB-65248: IF1 bound bovine ATP synthase monomer: rotary state 1 Method: EM (single particle) / Resolution: 2.4 Å EMDB-65249: IF1 bound bovine ATP synthase monomer: rotary state 1, Fo focused map Method: EM (single particle) / Resolution: 3.1 Å
Chemicals	ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying moleculeYM ChemComp-MG: Unknown entry ChemComp-ADP: ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying moleculeYM ChemComp-HOH: WATER
Source	bos taurus (domestic cattle)
Keywords	MEMBRANE PROTEIN / ATP synthase/hydrolase / oligomer / membrane bending / mammalian mitochondria / motor protein