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TitleAnimal and bacterial viruses share conserved mechanisms of immune evasion.
Journal, issue, pagesCell, Vol. 187, Page 5530-5539.e8, Year 2024
Publish dateApr 29, 2024 (structure data deposition date)
AuthorsHobbs, S.J. / Nomburg, J. / Doudna, J.A. / Kranzusch, P.J.
External linksCell / PubMed:39197447
MethodsX-ray diffraction
Resolution2.1 - 2.4 Å
Structure data

PDB-9bkq:
Structure of penguinpox cGAMP PDE in apo and post reaction states
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-9ciw:
Penguinpox cGAMP PDE H72A mutant in complex with 2'3'-cGAMP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

PDB-1aqn:
SUBTILISIN MUTANT 8324

ChemComp-GUN:
GUANINE

ChemComp-HOH:
WATER

PDB-1awu:
CYPA COMPLEXED WITH HVGPIA (PSEUDO-SYMMETRIC MONOMER)

Source
  • penguinpox virus
KeywordsVIRAL PROTEIN / Immune evasion / phosphodiesterase / poxvirus

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