EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6 beta-Hydroxylase.
ジャーナル・号・ページ	J. Am. Chem. Soc., Vol. 146, Page 24271-24287, Year 2024
掲載日	2022年5月18日 (構造データの登録日)
著者	Wenger, E.S. / Martinie, R.J. / Ushimaru, R. / Pollock, C.J. / Sil, D. / Li, A. / Hoang, N. / Palowitch, G.M. / Graham, B.P. / Schaperdoth, I. ...Wenger, E.S. / Martinie, R.J. / Ushimaru, R. / Pollock, C.J. / Sil, D. / Li, A. / Hoang, N. / Palowitch, G.M. / Graham, B.P. / Schaperdoth, I. / Burke, E.J. / Maggiolo, A.O. / Chang, W.C. / Allen, B.D. / Krebs, C. / Silakov, A. / Boal, A.K. / Bollinger Jr., J.M.
リンク	J. Am. Chem. Soc. / PubMed:39172701
手法	X線回折
解像度	1.53 - 2.03 Å
構造データ	PDB-8cv8: Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.532 Å PDB-8cv9: Structure of Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.79 Å PDB-8cva: Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, succinate, and 6-OH-hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.581 Å PDB-8cvb: Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and 6-OH-hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.532 Å PDB-8cvc: Structure of Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and 6-OH-hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.791 Å PDB-8cvd: Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, succinate, and scopolamine 手法: X-RAY DIFFRACTION / 解像度: 1.717 Å PDB-8cve: Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.53 Å PDB-8cvf: Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.532 Å PDB-8cvg: Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with iron, 2-oxoglutarate, and 6-OH-hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 1.56 Å PDB-8cvh: Structure of L289F Hyoscyamine 6-beta Hydroxylase in complex with vanadyl, succinate, and 6-OH-hyoscyamine 手法: X-RAY DIFFRACTION / 解像度: 2.03 Å
化合物	ChemComp-SR: STRONTIUM ION / ストロンチウムジカチオン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-FMT: FORMIC ACID / ギ酸 ChemComp-FE2: Unknown entry ChemComp-AKG: 2-OXOGLUTARIC ACID / α-ケトグルタル酸 ChemComp-HYO: [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate / alkaloid, toxinYM ChemComp-HOH: WATER ChemComp-SIN: SUCCINIC ACID / コハク酸 ChemComp-V: VANADIUM ION ChemComp-O: OXYGEN ATOM / 水 ChemComp-OVR: (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate / アニソダミン ChemComp-OW0*: (1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate
由来	atropa belladonna (ナス科)
キーワード	OXIDOREDUCTASE / oxacyclase / scopolamine / epoxide