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Structure paper

TitleMolecular basis for PHF7-mediated ubiquitination of histone H3.
Journal, issue, pagesGenes Dev., Vol. 37, Page 984-997, Year 2023
Publish dateJun 29, 2023 (structure data deposition date)
AuthorsLee, H.S. / Bang, I. / You, J. / Jeong, T.K. / Kim, C.R. / Hwang, M. / Kim, J.S. / Baek, S.H. / Song, J.J. / Choi, H.J.
External linksGenes Dev. / PubMed:37993255
MethodsX-ray diffraction
Resolution2 - 3.58 Å
Structure data

PDB-8jwj:
PHD Finger Protein 7 (PHF7) in complex with UBE2D2
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

PDB-8jws:
ePHD domain of PHD Finger Protein 7 (PHF7)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-8jwu:
PHD Finger Protein 7 (PHF7) fused to UBE2D2 via a (GSGG)3 linker
Method: X-RAY DIFFRACTION / Resolution: 3.58 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsLIGASE / Ubiquitin / RING ligase / PHD / complex / ePHD / linker

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