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TitleDifferential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Journal, issue, pagesNat Commun, Vol. 13, Page 1207-1207, Year 2022
Publish dateJan 14, 2021 (structure data deposition date)
AuthorsFlorio, T.J. / Lokareddy, R.K. / Yeggoni, D.P. / Sankhala, R.S. / Ott, C.A. / Gillilan, R.E. / Cingolani, G.
External linksNat Commun / PubMed:35260573
MethodsX-ray diffraction
Resolution2.1 - 2.85 Å
Structure data

PDB-7leq:
Structure of importin a2 bound to p50 NLS
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

PDB-7let:
Structure of importin a2 bound to the p50- and p65-NLSs
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-7leu:
Structure of importin a2 bound to p65-NLS
Method: X-RAY DIFFRACTION / Resolution: 2.82 Å

PDB-7lf4:
Structure of importin a3 bound to the p50- and p65-NLSs
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-7lfc:
Structure of importin a3 bound to p50 NLS
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / NUCLEAR IMPORT / IMPORTIN ALPHA / NLS / NF-kB / p50 / p65 / IMPORTIN ALPHA 3

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