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Structure paper

TitleThe shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Journal, issue, pagesSci Immunol, Vol. 6, Year 2021
Publish dateNov 19, 2019 (structure data deposition date)
AuthorsLim, J.J. / Jones, C.M. / Loh, T.J. / Ting, Y.T. / Zareie, P. / Loh, K.L. / Felix, N.J. / Suri, A. / McKinnon, M. / Stevenaert, F. ...Lim, J.J. / Jones, C.M. / Loh, T.J. / Ting, Y.T. / Zareie, P. / Loh, K.L. / Felix, N.J. / Suri, A. / McKinnon, M. / Stevenaert, F. / Sharma, R.K. / Klareskog, L. / Malmstrom, V. / Baker, D.G. / Purcell, A.W. / Reid, H.H. / La Gruta, N.L. / Rossjohn, J.
External linksSci Immunol / PubMed:33863750
MethodsX-ray diffraction
Resolution2.29 - 2.8 Å
Structure data

PDB-6v0y:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-6v13:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-6v15:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-6v18:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-6v19:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6v1a:
immune receptor complex
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Immune receptor / Complex

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