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Structure paper

TitleStructural Basis for the Binding Selectivity of Human CDY Chromodomains.
Journal, issue, pagesCell Chem Biol, Vol. 27, Page 827-838.e7, Year 2020
Publish dateDec 28, 2013 (structure data deposition date)
AuthorsDong, C. / Liu, Y. / Lyu, T.J. / Beldar, S. / Lamb, K.N. / Tempel, W. / Li, Y. / Li, Z. / James, L.I. / Qin, S. ...Dong, C. / Liu, Y. / Lyu, T.J. / Beldar, S. / Lamb, K.N. / Tempel, W. / Li, Y. / Li, Z. / James, L.I. / Qin, S. / Wang, Y. / Min, J.
External linksCell Chem Biol / PubMed:32470319
MethodsNMR (solution) / X-ray diffraction
Resolution1.6 - 2.8 Å
Structure data

PDB-2mj8:
Solution structure of CDYL2 chromodomain
Method: SOLUTION NMR

PDB-6v2d:
Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6v2h:
Crystal structure of CDYL2 in complex with H3tK27me3
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6v2r:
Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6v2s:
Crystal Structure of chromodomain of MPP8 in complex with inhibitor UNC3866
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6v3n:
Crystal structure of CDYL2 in complex with H3K27me3
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-6v41:
crystal structure of CDY1 chromodomain bound to H3K9me3
Method: X-RAY DIFFRACTION / Resolution: 1.603 Å

PDB-6v8w:
CDYL2 chromodomain in complex with a synthetic peptide
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsPROTEIN BINDING / chromodomain / Structural Genomics / Structural Genomics Consortium / SGC / GENE REGULATION / histone / epigenetics / TRANSFERASE

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