EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
ジャーナル・号・ページ	Acs Chem. Biol., Vol. 15, Page 407-415, Year 2020
掲載日	2018年8月20日 (構造データの登録日)
著者	Pang, L. / Nautiyal, M. / De Graef, S. / Gadakh, B. / Zorzini, V. / Economou, A. / Strelkov, S.V. / Van Aerschot, A. / Weeks, S.D.
リンク	Acs Chem. Biol. / PubMed:31869198
手法	X線回折
解像度	1.84 - 2.41 Å
構造データ	PDB-6hdz: Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine 手法: X-RAY DIFFRACTION / 解像度: 2.06 Å PDB-6he1: Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine 手法: X-RAY DIFFRACTION / 解像度: 2.22 Å PDB-6he3: Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine 手法: X-RAY DIFFRACTION / 解像度: 2.16 Å PDB-6hhv: Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine 手法: X-RAY DIFFRACTION / 解像度: 2.18 Å PDB-6hhw: Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-6hhx: Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-6hhy: Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine 手法: X-RAY DIFFRACTION / 解像度: 2.27 Å PDB-6hhz: Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-6hi0: Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-6rlt: Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine 手法: X-RAY DIFFRACTION / 解像度: 1.84 Å PDB-6rlu: Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine 手法: X-RAY DIFFRACTION / 解像度: 1.88 Å PDB-6rlv: Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-6s30: Crystal Structure of Seryl-tRNA Synthetase from Klebsiella pneumoniae 手法: X-RAY DIFFRACTION / 解像度: 2.41 Å PDB-6sjc: Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine 手法: X-RAY DIFFRACTION / 解像度: 2.23 Å
化合物	ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-FZK: 5'-O-(N-(L-seryl)-Sulfamoyl)uridine ChemComp-NA: Unknown entry ChemComp-HOH: WATER ChemComp-FZT: 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine ChemComp-FZQ: 5'-O-(N-(L-seryl)-sulfamoyl)cytidine ChemComp-G5Q: 5'-O-(N-(L-aspartyl)-sulfamoyl)N3-methyluridine ChemComp-G5H: 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine ChemComp-G5N: 5'-O-(N-(L-aspartyl)-sulfamoyl)cytidine ChemComp-CA: Unknown entry ChemComp-CL: Unknown entry ChemComp-1PE: PENTAETHYLENE GLYCOL / 沈殿剤YM ChemComp-GOL: GLYCEROL ChemComp-MLI: MALONATE ION ChemComp-DSZ*: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine
由来	pseudomonas aeruginosa (緑膿菌) thermus thermophilus (バクテリア) klebsiella pneumoniae (肺炎桿菌) trypanosoma brucei gambiense (ガンビアトリパノソーマ)
キーワード	LIGASE / Coil-coil / Beta barrel / tRNA Synthetase / Inhibitor / Complex / protein-inhibitor complex / tRNA aminoacylation