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Structure paper

TitleStructural Basis of an Asymmetric Condensin ATPase Cycle.
Journal, issue, pagesMol. Cell, Vol. 74, Page 1175-1188.e9, Year 2019
Publish dateDec 10, 2018 (structure data deposition date)
AuthorsHassler, M. / Shaltiel, I.A. / Kschonsak, M. / Simon, B. / Merkel, F. / Tharichen, L. / Bailey, H.J. / Macosek, J. / Bravo, S. / Metz, J. ...Hassler, M. / Shaltiel, I.A. / Kschonsak, M. / Simon, B. / Merkel, F. / Tharichen, L. / Bailey, H.J. / Macosek, J. / Bravo, S. / Metz, J. / Hennig, J. / Haering, C.H.
External linksMol. Cell / PubMed:31226277
MethodsNMR (solution) / X-ray diffraction
Resolution2 - 5.8 Å
Structure data

PDB-6q6e:
Structural and functional insights into the condensin ATPase cycle
Method: SOLUTION NMR

PDB-6qj0:
Crystal structure of the C. thermophilum condensin Smc2 ATPase head (crystal form II)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6qj1:
Crystal structure of the C. thermophilum condensin Smc2 ATPase head (crystal from I)
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-6qj2:
Crystal structure of the C. thermophilum condensin Smc4 ATPase head in complex with the C-terminal domain of Brn1
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6qj3:
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-6qj4:
Crystal structure of the C. thermophilum condensin Ycs4-Brn1 subcomplex bound to the Smc4 ATPase head in complex with the C-terminal domain of Brn1
Method: X-RAY DIFFRACTION / Resolution: 5.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • chaetomium thermophilum (fungus)
  • chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719) (fungus)
KeywordsSTRUCTURAL PROTEIN / Condensin / cohesin / SMC protein complex / CELL CYCLE / condensin SMC complex ATPase chromosome condensation loop extrusion / SMC complex / ATPase / chromosome condensation / loop extrusion

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