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Structure paper

TitleStructural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Journal, issue, pagesNat Commun, Vol. 9, Page 4458-4458, Year 2018
Publish dateJul 23, 2018 (structure data deposition date)
AuthorsKundu, P. / Semesi, A. / Jore, M.M. / Morin, M.J. / Price, V.L. / Liang, A. / Li, J. / Miura, K. / Sauerwein, R.W. / King, C.R. / Julien, J.P.
External linksNat Commun / PubMed:30367064
MethodsX-ray diffraction
Resolution1.5 - 3.15 Å
Structure data

PDB-6e62:
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-6e63:
Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6e64:
Crystal structure of malaria transmission-blocking antibody 85RF45.1
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-6e65:
Crystal structure of malaria transmission-blocking antibody TB31F
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / malaria / transmission-blocking / antigen / antibody

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