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Structure paper

TitleStructural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
Journal, issue, pagesJ. Neurochem., Vol. 145, Page 449-463, Year 2018
Publish dateAug 28, 2017 (structure data deposition date)
AuthorsPonna, S.K. / Ruskamo, S. / Myllykoski, M. / Keller, C. / Boeckers, T.M. / Kursula, P.
External linksJ. Neurochem. / PubMed:29473168
MethodsX-ray diffraction
Resolution1.4 - 2.3 Å
Structure data

PDB-5ova:
Apo PDZ domain from rat Shank3
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5ovc:
PDZ domain from rat Shank3 bound to the C terminus of GKAP
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-5ovp:
PDZ domain from rat Shank3 bound to the C terminus of CIRL
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-5ovv:
PDZ domain from rat Shank3 bound to the C terminus of ProSAPiP1
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-6exj:
PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-SCN:
THIOCYANATE ION

Source
  • rattus norvegicus (Norway rat)
KeywordsPROTEIN BINDING / PDZ domain / peptide binding / post-synaptic density / C terminus

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