タイトル | Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. |
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ジャーナル・号・ページ | Structure, Vol. 24, Page 2053-2066, Year 2016 |
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掲載日 | 2013年12月9日 (構造データの登録日) |
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著者 | Liu, X. / Speckhard, D.C. / Shepherd, T.R. / Sun, Y.J. / Hengel, S.R. / Yu, L. / Fowler, C.A. / Gakhar, L. / Fuentes, E.J. |
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リンク | Structure / PubMed:27998539 |
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手法 | X線回折 |
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解像度 | 1.9 - 2.3 Å |
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構造データ | PDB-4nxp: Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4nxq: Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4nxr: Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Neurexin-1 Peptide 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å |
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化合物 | ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤*YM / HEPES
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由来 | ![](img/tx_human.gif) homo sapiens (ヒト)
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キーワード | SIGNALING PROTEIN / Beta barrel fold protein / PDZ domain (PDZドメイン) / peptide binding (ペプチド) / specificity mutant / scaffold signaling protein for cell adhesion and cell junction / signaling domain / signaling Protein/Peptide / PDZ domain; peptide binding (PDZドメイン) / protein-peptide complex / signaling Protein-Peptide complex |
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