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Structure paper

TitleThe Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Journal, issue, pagesMol. Cell, Vol. 64, Page 467-479, Year 2016
Publish dateAug 29, 2016 (structure data deposition date)
AuthorsGruner, S. / Peter, D. / Weber, R. / Wohlbold, L. / Chung, M.Y. / Weichenrieder, O. / Valkov, E. / Igreja, C. / Izaurralde, E.
External linksMol. Cell / PubMed:27773676
MethodsX-ray diffraction
Resolution1.53 - 2.2 Å
Structure data

PDB-5t46:
Crystal structure of the human eIF4E-eIF4G complex
Method: X-RAY DIFFRACTION / Resolution: 1.53 Å

PDB-5t47:
Crystal structure of the D. melanogaster eIF4E-eIF4G complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5t48:
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • drosophila melanogaster (fruit fly)
KeywordsTRANSLATION / GENE REGULATION / CAP BINDING PROTEIN / 4E-BINDING PROTEIN / TRANSLATION INITIATION / eIF4F

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