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Structure paper

TitleMolecular basis of sidekick-mediated cell-cell adhesion and specificity.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateMay 25, 2016 (structure data deposition date)
AuthorsGoodman, K.M. / Yamagata, M. / Jin, X. / Mannepalli, S. / Katsamba, P.S. / Ahlsen, G. / Sergeeva, A.P. / Honig, B. / Sanes, J.R. / Shapiro, L.
External linksElife / PubMed:27644106
MethodsX-ray diffraction
Resolution2.201 - 3.5 Å
Structure data

PDB-5k6u:
Sidekick-1 immunoglobulin domains 1-4, crystal form 1
Method: X-RAY DIFFRACTION / Resolution: 2.201 Å

PDB-5k6v:
Sidekick-1 immunoglobulin domains 1-4, crystal form 2
Method: X-RAY DIFFRACTION / Resolution: 3.208 Å

PDB-5k6w:
Sidekick-1 immunoglobulin domains 1-5
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-5k6x:
Sidekick-2 immunoglobulin domains 1-4, crystal form 1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5k6y:
Sidekick-2 immunoglobulin domains 1-4, crystal form 2
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-5k6z:
Sidekick chimera containing sidekick-2 immunoglobulin domains 1-2 and sidekick-1 immunoglobulin domains 3-4
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5k70:
Sidekick-2 immunoglobulin domains 1-4 H18R/N22S mutant
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-CS:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-CAC:
CACODYLATE ION

ChemComp-PO4:
PHOSPHATE ION

Source
  • mus musculus (house mouse)
KeywordsCELL ADHESION / immunoglobulin

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