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TitleActivation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
Journal, issue, pagesStructure, Vol. 24, Page 1729-1741, Year 2016
Publish dateJun 23, 2015 (structure data deposition date)
AuthorsDominguez-Gil, T. / Lee, M. / Acebron-Avalos, I. / Mahasenan, K.V. / Hesek, D. / Dik, D.A. / Byun, B. / Lastochkin, E. / Fisher, J.F. / Mobashery, S. / Hermoso, J.A.
External linksStructure / PubMed:27618662
MethodsX-ray diffraction
Resolution1.801 - 3.2 Å
Structure data

PDB-5a5x:
Crystal Structure of Se-Met MltF from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.801 Å

PDB-5aa1:
Crystal structure of MltF from Pseudomonas aeruginosa in complex with NAG-anhNAM-pentapeptide
Method: X-RAY DIFFRACTION / Resolution: 2.89 Å

PDB-5aa2:
Crystal structure of MltF from Pseudomonas aeruginosa in complex with NAM-pentapeptide.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5aa3:
Crystal structure of MltF from Pseudomonas aeruginosa in the presence of tetrasaccharide and tetrapeptide
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-5aa4:
Crystal structure of MltF from Pseudomonas aeruginosa in complex with cell-wall tetrapeptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-6X4:
[6-[[(2~{R})-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-6-oxidanylidene-5-[[(4~{R})-5-oxidanyl-5-oxidanylidene-4-[[(2~{S})-2-[[(2~{R})-2-oxidanylpropanoyl]amino]propanoyl]amino]pentanoyl]amino]hexyl]azanium

Source
  • pseudomonas aeruginosa pao1 (bacteria)
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / LYTIC TRANSGLYCOSILOSE / CELL WALL RECYCLING / LYASE / LYTIC TRANSGLYCOSILASE / PSEUDOMONAS AERUGINOSA / SUGAR BINDING PROTEIN

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