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Structure paper

TitleDna2 nuclease-helicase structure, mechanism and regulation by Rpa.
Journal, issue, pagesElife, Vol. 4, Year 2015
Publish dateOct 16, 2015 (structure data deposition date)
AuthorsZhou, C. / Pourmal, S. / Pavletich, N.P.
External linksElife / PubMed:26491943
MethodsX-ray diffraction
Resolution1.55 - 3.05 Å
Structure data

PDB-5ean:
Crystal structure of Dna2 in complex with a 5' overhang DNA
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-5eaw:
Crystal structure of Dna2 nuclease-helicase
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5eax:
Crystal structure of Dna2 in complex with an ssDNA
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-5eay:
Crystal structure of a Dna2 peptide in complex with Rpa 70N
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-CA:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsHydrolase/DNA / DNA binding protein / Hydrolase-DNA complex / HYDROLASE

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