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TitleNeuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 18744-18756, Year 2015
Publish dateMar 15, 2015 (structure data deposition date)
AuthorsPandalaneni, S. / Karuppiah, V. / Saleem, M. / Haynes, L.P. / Burgoyne, R.D. / Mayans, O. / Derrick, J.P. / Lian, L.Y.
External linksJ. Biol. Chem. / PubMed:25979333
MethodsX-ray diffraction
Resolution1.95 - 2.8 Å
Structure data

PDB-4yru:
Crystal structure of C-terminally truncated Neuronal Calcium Sensor (NCS-1) from Rattus norvegicus
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5aeq:
Neuronal calcium sensor (NCS-1)from Rattus norvegicus
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-5aer:
Neuronal calcium sensor-1 (NCS-1)from Rattus norvegicus complex with D2 dopamine receptor peptide from Homo sapiens
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

PDB-5afp:
Neuronal calcium sensor-1 (NCS-1)from Rattus norvegicus complex with rhodopsin kinase peptide from Homo sapiens
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-K:
Unknown entry

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / EF-hand / Calcium sensor / C-terminal truncation / NEURONAL CALCIUM SENSOR-1 / DOPAMINE RECEPTOR 2

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