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Structure paper

TitleStructural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Journal, issue, pagesNat Commun, Vol. 5, Page 3952-3952, Year 2014
Publish dateDec 5, 2013 (structure data deposition date)
AuthorsQin, S. / Liu, Y. / Tempel, W. / Eram, M.S. / Bian, C. / Liu, K. / Senisterra, G. / Crombet, L. / Vedadi, M. / Min, J.
External linksNat Commun / PubMed:24853335
MethodsX-ray diffraction
Resolution1.87 - 2.9 Å
Structure data

PDB-4nw2:
Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4o42:
Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4o45:
WDR5 in complex with influenza NS1 C-terminal tail
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4o46:
14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-UNX:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • influenza a virus
  • influenza a virus h3n2
KeywordsPEPTIDE BINDING PROTEIN/VIRAL PROTEIN / Structural Genomics Consortium / SGC / PEPTIDE BINDING PROTEIN-VIRAL PROTEIN complex / DNA BINDING PROTEIN/VIRAL PROTEIN / viral / chromodomain / Structural Genomics / DNA BINDING PROTEIN-VIRAL PROTEIN complex / TRANSCRIPTION/RNA BINDING PROTEIN / TRANSCRIPTION-RNA BINDING PROTEIN complex / VIRAL PROTEIN / influenza

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