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TitleStructural Elucidation of the Mechanistic Basis of Degeneracy in the Primary Humoral Response.
Journal, issue, pagesJ. Immunol., Vol. 188, Page 1819-, Year 2012
Publish dateDec 1, 2010 (structure data deposition date)
AuthorsKhan, T. / Salunke, D.M.
External linksJ. Immunol. / PubMed:22266283
MethodsX-ray diffraction
Resolution2.4 - 2.9 Å
Structure data

PDB-2xzq:
CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-(4-HYDROXY-3-NITROPHENYL)- ACETYL MURINE GERMLINE MONOCLONAL ANTIBODY BBE6.12H3 FAB FRAGMENT IN COMPLEX WITH A PHAGE DISPLAY DERIVED DODECAPEPTIDE YQLRPNAETLRF
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2y06:
CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-(4-HYDROXY-3-NITROPHENYL) - ACETYL MURINE GERMLINE ANTIBODY BBE6.12H3 FAB FRAGMENT IN COMPLEX WITH A PHAGE DISPLAY DERIVED DODECAPEPTIDE GDPRPSYISHLL
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2y07:
CRYSTAL STRUCTURE ANALYSIS OF THE ANTI-(4-HYDROXY-3-NITROPHENYL) - ACETYL MURINE GERMLINE MONOCLONAL ANTIBODY BBE6.12H3 FAB FRAGMENT IN COMPLEX WITH A PHAGE DISPLAY DERIVED DODECAPEPTIDE PPYPAWHAPGNI
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2y36:
Crystal structure analysis of the anti-(4-hydroxy-3-nitrophenyl)- acetyl murine germline antibody BBE6.12H3 Fab fragment in complex with a phage display derived dodecapeptide DLWTTAIPTIPS
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4a6y:
CRYSTAL STRUCTURE OF FAB FRAGMENT OF ANTI-(4-HYDROXY-3-NITROPHENYL) -ACETYL MURINE GERMLINE ANTIBODY BBE6.12H3
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / BETA-SANDWICH IMMUNOGLOBULIN FOLD / ANTIGEN BINDING / SECRETED PROTEIN / ANTIBODY MULTISPECIFICITY / HUMORAL IMMUNE SYSTEM / COMPLEMENTARITY DETERMINING REGION FLEXIBILITY

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