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Structure paper

TitleA Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Journal, issue, pagesNature, Vol. 468, Page 108-, Year 2010
Publish dateNov 11, 2009 (structure data deposition date)
AuthorsZhou, A. / Carrell, R.W. / Murphy, M.P. / Wei, Z. / Yan, Y. / Stanley, P.L. / Stein, P.E. / Pipkin, F.B. / Read, R.J.
External linksNature / PubMed:20927107
MethodsX-ray diffraction
Resolution2.1 - 4.33 Å
Structure data

PDB-2wxw:
Crystal structure of human angiotensinogen
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-2wxx:
Crystal structure of mouse angiotensinogen in the oxidised form
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-2wxy:
Crystal structure of mouse angiotensinogen in the reduced form
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2wxz:
Crystal structure of rat angiotensinogen in C2 space group
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2wy0:
Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-2wy1:
Crystal structure of rat angiotensinogen in P321 space group
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-2x0b:
Crystal structure of human angiotensinogen complexed with renin
Method: X-RAY DIFFRACTION / Resolution: 4.33 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
  • rattus norvegicus (Norway rat)
KeywordsHORMONE / GLYCOPROTEIN / HYPERTENSION / VASOCONSTRICTOR / RENIN / SERPINS / VASOACTIVE / ANGIOTENSIN / ANGIOTENSINOGEN / HYDROLASE/HORMONE / HYDROLASE-HORMONE COMPLEX / HYDROLASE HORMONE COMPLEX / ZYMOGEN / HYDROLASE

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