タイトル | Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation. |
---|
ジャーナル・号・ページ | J. Biol. Chem., Vol. 285, Page 38204-, Year 2010 |
---|
掲載日 | 2009年10月30日 (構造データの登録日) |
---|
著者 | Froese, D.S. / Kochan, G. / Muniz, J.R.C. / Wu, X. / Gileadi, C. / Ugochukwu, E. / Krysztofinska, E. / Gravel, R.A. / Oppermann, U. / Yue, W.W. |
---|
リンク | J. Biol. Chem. / PubMed:20876572 |
---|
手法 | X線回折 |
---|
解像度 | 1.95 - 2.64 Å |
---|
構造データ | PDB-2www: Crystal Structure of Methylmalonic Acidemia Type A Protein 手法: X-RAY DIFFRACTION / 解像度: 2.64 Å PDB-2xij: Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-2xiq: Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-3bic: Crystal structure of human methylmalonyl-CoA mutase 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å |
---|
化合物 | ChemComp-GDP: GUANOSINE-5'-DIPHOSPHATE / GDP / GDP, エネルギー貯蔵分子*YM / グアノシン二リン酸
ChemComp-BTB: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / ビストリス / pH緩衝剤*YM / Bis-tris methane
|
---|
由来 | ![](img/tx_human.gif) homo sapiens (ヒト)
|
---|
キーワード | TRANSPORT PROTEIN (運搬体タンパク質) / NUCLEOTIDE-BINDING / ISOMERASE (異性化酵素) / ORGANIC ACIDURIA / VITAMIN B12 (コバラミン) / METABOLIC DISEASE (代謝異常) / methylmalonyl CoA mutase deficiency / Structural Genomics (構造ゲノミクス) / Structural Genomics Consortium / SGC / Cobalamin (コバラミン) / Cobalt (コバルト) / Disease mutation / Metal-binding / Mitochondrion (ミトコンドリア) / Transit peptide |
---|