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Structure paper

TitleCrystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Journal, issue, pagesPlos One, Vol. 5, Page e8625-e8625, Year 2010
Publish dateNov 27, 2008 (structure data deposition date)
AuthorsWisniewska, M. / Karlberg, T. / Lehtio, L. / Johansson, I. / Kotenyova, T. / Moche, M. / Schueler, H.
External linksPlos One / PubMed:20072699
MethodsX-ray diffraction
Resolution1.3 - 2.4 Å
Structure data

PDB-3fe1:
Crystal structure of the human 70kDa heat shock protein 6 (Hsp70B') ATPase domain in complex with ADP and inorganic phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3gdq:
Crystal structure of the human 70kDa heat shock protein 1-like ATPase domain in complex with ADP and inorganic phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3i33:
Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in complex with ADP and inorganic phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-3iuc:
Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3jxu:
Crystal structure of the human 70kDa heat shock protein 1A (Hsp70-1) ATPase domain in complex with ADP and inorganic phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-MN:
Unknown entry

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCHAPERONE / mixed beta-sheet / ATP-binding / Nucleotide-binding / Polymorphism / Stress response / Structural Genomics / Structural Genomics Consortium / SGC / helix / TRANSCRIPTION / protein-ADP complex / Phosphoprotein

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