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TitleA promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 17, Page 105-111, Year 2010
Publish dateJul 8, 2009 (structure data deposition date)
AuthorsLi, T. / Robert, E.I. / van Breugel, P.C. / Strubin, M. / Zheng, N.
External linksNat. Struct. Mol. Biol. / PubMed:19966799
MethodsX-ray diffraction
Resolution2.8 - 3.4 Å
Structure data

PDB-3i7h:
Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3i7k:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3i7l:
Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3i7n:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3i7o:
Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3i7p:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3i89:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3i8c:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3i8e:
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Source
  • homo sapiens (human)
  • human hepatitis b virus
  • woodchuck hepatitis b virus
KeywordsPROTEIN BINDING/VIRAL PROTEIN / DDB1 / HBV / X protein / H-Box Motif / Cytoplasm / DNA damage / DNA repair / DNA-binding / Host-virus interaction / Nucleus / Phosphoprotein / Polymorphism / Ubl conjugation / Ubl conjugation pathway / Activator / Apoptosis / Mitochondrion / Transcription / Transcription regulation / PROTEIN BINDING-VIRAL PROTEIN COMPLEX / PROTEIN BINDING / DDB2 / Alternative splicing / Disease mutation / WD repeat / Xeroderma pigmentosum / WDTC1 / DCAF9 / TPR repeat / IQWD1 / DCAF6 / WDR40A / DCAF12 / WDR22 / DCAF5 / WDR21A / DCAF4 / WDR42A / H326 / DCAF8

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