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TitleCrystal Structure of Thermotoga Maritima Alpha-L-Fucosidase. Insights Into the Catalytic Mechanism and the Molecular Basis for Fucosidosis.
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 13119-, Year 2004
Publish dateMar 14, 2003 (structure data deposition date)
AuthorsSulzenbacher, G. / Bignon, C. / Nishimura, T. / Tarling, C.A. / Withers, S.G. / Henrissat, B. / Bourne, Y.
External linksJ. Biol. Chem. / PubMed:14715651
MethodsX-ray diffraction
Resolution2.25 - 2.8 Å
Structure data

PDB-1hl8:
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1hl9:
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE IN COMPLEX WITH A MECHANISM BASED INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-1odu:
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE IN COMPLEX WITH FUCOSE
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FUF:
2-deoxy-2-fluoro-beta-L-fucopyranose

ChemComp-FUL:
beta-L-fucopyranose

Source
  • thermotoga maritima (bacteria)
KeywordsHYDROLASE / GLYCOSIDE HYDROLASE / ALPHA-L-FUCOSIDASE / THERMOSTABLE / GLYCOSYL-ENZYME INTERMEDIATE / PRODUCT COMPLEX

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