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TitleAnthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.
Journal, issue, pagesJ. Clin. Invest., Vol. 127, Issue 8, Page 2957-2967, Year 2017
Publish dateAug 1, 2017
AuthorsLinde A Miles / Laura N Burga / Eric E Gardner / Mihnea Bostina / John T Poirier / Charles M Rudin
External linksPubMed:28650343 / Publisher's page
KeywordsANTXR1 protein, human / Animals / Capsid Proteins / Cell Line, Tumor / Cell Survival / Cryoelectron Microscopy / Female / Gene Expression Profiling / Genome / Green Fluorescent Proteins / Humans / Mice / Mice, Nude / Neoplasm Proteins / Oncolytic Virotherapy / Oncolytic Viruses / Picornaviridae / Receptors, Cell Surface / Receptors, Virus
MethodsEM (single particle, icos. sym.)
Resolution18 A
Structure data

EMDB-3303:
Cryo-EM reconstruction of Seneca VAlley Virus - receptor complex

Source
  • Seneca valley virus

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    • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
    • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
    • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

    External links: The 2017 Nobel Prize in Chemistry - Press Release

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